You need to be a little more specific, ISO is a fairly general term, as Jack Frost mentioned, there is an ISO with the file extension ".iso", in which case you use the programs he mentioned. There are also others, however, .bin, .img, etc., which are somewhat program specific. CloneCD uses the .img format, and there are several that handle the .bin format, CDRWIN, Nero(I think) & Fireburner, if there's any others I can't remember them right now. For specific instructions, you need to know what the file extension is of your ISO, let us know.
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